产品货号：
Z14566
中文名称：
FLIP/CFLAR抗体
英文名称：
Anti-FLIP/CFLAR Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FLIP/CFLAR Antibody |
| 指标别名 | c FLIP;c FLIPL;c FLIPR;c FLIPS;CASH;CASP8AP1;Caspase eight related protein;Caspase homolog;Casper;CFLAR;CFLAR/FLIP;CLARP;FLAME;FLAME 1;FLAME1;FLIP;I FLICE;Inhibitor of FLICE;MRIT;Usurpin |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,ICC,IF,FCM |
| 基因名称 | CFLAR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FLIP antibody was raised against a peptide corresponding to 17 amino acids near the amino terminus of human FLIP.The sequence is identical in all FLIP splice variants.The immunogen is located within the first 50 amino acids of FLIP. |
| 计算分子量 | 55kDa |
| 成分 | FLIP Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FLIP Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family.Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family.FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP,respectively.The human FLIP was also cloned by several labs independently and termed Casper,I-FLICE,FLAME-1,CASH and CLARP3-7.FLIP contains two death effector domains (DEDs) and a caspase-like domain.FLIP interacts with adapter protein FADD and caspase-8 and 10,and potently inhibits apoptosis induced by all known death receptors.Four splice variants of c-FLIPs have been identified and termed FLIPalpha,beta,gamma,and delta,respectively. |
| Uniprot ID | O15519 |
| 基因名全称 | CASP8 and FADD-like apoptosis regulator |
| 蛋白名全称 | CASP8 and FADD-like apoptosis regulator |
| 推荐稀释比 | FLIP antibody can be used for Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 5μg/mL and immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunohistochemistry in mouse samples;Immunocytochemistry in human samples and Immunofluorescence in human and mouse samples.All other applications and species not yet tested. |
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